T20/C4 Indica

THC: 23%-24%

CBD: <1%

Plant Type: Indica – dominant

Genetic Similarity: Critical Kush

Combo is an Indica-dominant strain, developed as part of Canonic’s premium variety program and it contains a pointed inflorescence structure, with abundant flowers at a high concentration of trichomes that produce an extraordinary glaze. As part of our unique cultivation program, we measure hundreds of different traits of each variety to comprehensively profile the fragrances and aromas, until reaching a high-level, precise and unique combination.

Genetic uniqueness:

For the first time in Israel, Canonic has conducted  genomic mapping of publicly available cannabis genomes, collected worldwide, and compared the new varieties to the worldwide genetics. This information has been shared with patients and displayed as comparative genetic similarity. The genomic analysis we performed for Combo indicates genetic similarity to the famous ‘Critical Kush’ strain.

Unlike unknown varieties released around the world, Canonic’s varieties are developed by a leading scientific and technological team of the best geneticists. Our vast knowledge and state of the art development facilities provide patients with quality, precision, and genetic similarity to the original varieties.



Dominant Terpenes

It is considered the most abundant terpene among the various cannabis strains, which is responsible for a sweet tropical flavor and an earthy aroma with a hint of the mask. Other than that, b-Myrcene is found in hops, thyme, bay leaves, parsley, and basil as well as in cardamom, lemon grass, mango, and Spanish lime fruits. b-Myrcene is considered as having sedative effects, and studies have demonstrated a reduction in stress and anxiety levels while elevating a sense of relaxation and calmness, energy levels, and mood. It likewise demonstrated pain relief and sleep induction potential together with strong antioxidant activity.


Being spicy and pungent, b-Caryophyllene conveys a pleasant warmth. This terpene is found in various aromatic plants and spices, such as black pepper, basil, oregano, cloves, rosemary, and cinnamon, as well as in popular cannabis strains such as Girl Scout Cookies. b-Caryophyllene is the only terpene that acts within the body like a cannabinoid. It affects the cannabinoid system by binding to CB2 receptors throughout the body, and it likewise has an anti-inflammatory effect.


a-Humulene is a with an earthy-woody aroma. Its name is derived from the plant Hummulus Lupulus which belongs to the same botanic family as the cannabis plant, and it is likewise found in sage and ginseng roots.  a-Humulene constitutes part of the defense mechanism of the cannabis plant against various pests, due to its strong anti-microbial activity. Preliminary studies demonstrated anti-oxidant, anti-inflammatory, gastro-protective, and appetite suppression potential.

Limonene is the most abundant terpene in nature. It is the main constituent in citrus peel essential oil (orange, lemon, lime, grapefruit, and mandarins) having a strong citrus-lemon aroma. According to research from 2018, not only THC but also certain terpenes contribute to the “high” and mood elevation effects that characterize various cannabis strains – due to the known ‘entourage effect’, and limonene is the terpene that is mostly associated with mood elevation and euphoria. This is the reason why limonene and other citrus scents are used in aromatherapy and the perfume industry for these purposes.  In one study, inhalation of limonene vapor increased serotonin and dopamine levels in key regions of the brain that are associated with anxiety, depression, and OCD. In addition, preliminary clinical studies have shown that limonene has the potential to dissolve gallstones, relieve heartburn due to its gastric-acid neutralizing effect and improve peristalsis. It has likewise demonstrated a partial benefice effect as part of the treatment of certain types of cancers.


Linalool is a terpene that is quite abundant in nature and is found in over 200 types of plants, including lavender, roses, basil, and neroli oil. It has a characteristic lavender-dominant aroma with some gentle hints of pungency. Plants produce linalool as part of their defense mechanism against pests, and this explains linalool’s strong anti-microbial properties and the fact that it is being studied as an anti-bacterial agent. In traditional herbal medicine, it is customary to use medicinal herbs containing linalool for calming and relaxing the body. And indeed, clinical research on lavender essential oil (of which linalool is a major constituent) has demonstrated a calming, stress-reducing effect. Additionally, in a clinical study with patients post gastric band surgery, inhaling linalool vapor had a significant analgesic effect.


Bisabolol is a terpene that was initially isolated from chamomile flowers where it is found in abundance. However, it exists in other plants as well, for example in micromeria and reishi mushrooms. It has a nutty-fruity aroma resembling that of coconut.  Preliminary clinical studies have indicated skin ulcer healing enhancement potential as well as relieving eczema and itching outbreaks when used topically. It has likewise demonstrated a significant anti-inflammatory effect. Studies in animal models have indicated neuroprotection potential due to a strong anti-oxidant and anti-inflammatory activity, as well as an analgesic and cardioprotective potential. Laboratory studies have demonstrated a broad spectrum of anti-microbial activity (against E.coli, candida, staphylococcus, and more).





Guaiol is a terpene with a characteristic piney aroma with notes of rose scents. It is found in abundance in the guaiacum tree, from which he got his name, and in Callitris. It has been used for many years in traditional herbal medicine as part of the treatment of various health conditions, including coughing, constipation, and arthritis, and it is attributed to its anti-inflammatory and anti-microbial activity. It is noteworthy, however, that the research on Guaiol is still very preliminary at this point.

Taste and Aroma


Patient feedback we received reported:


* This information herein does not constitute a binding opinion and should not be relied upon except as a general review, which is not a substitute for a professional medical opinion. CANONIC cannot guarantee and is not responsible that the effects described, or similar effects, will be felt by patients. The information should not be construed as advertisement and / or recommendation and / or encouragement for the use of cannabis, which is a prohibited use by law, other than for medical purposes. The use of medical cannabis is subject to the recommendation of a specialist doctor and in accordance with a suitable license from the Ministry of Health according to law.


Together with you:

You can help us develop better products! Canonic invites you to share with us experiences from the treatment. Combined with our extensive genetic databases, your feedback can help create strains that are better suited to patients’ needs. Join us and together we will improve the therapeutic experience.

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